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Biopharmaceutical Executive Placement

Precision
Leadership for
Capital-Critical
Moments

Boutique executive search for venture-backed and publicly traded biopharmaceutical companies — placing C-suite leaders at inflection points where quality of hire directly impacts valuation.

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C-Suite
& Functional Head Placements
National
U.S. Search Reach
Seed to Scale
Venture-Backed Through Large Pharma
Zero
Institutional Bureaucracy
01 — About

Who We Are

01

Blake & Michaels is a boutique executive search and advisory firm serving the full spectrum of the biopharmaceutical sector — from emerging venture-backed biotechs and mid-sized development-stage companies to established large pharma organizations navigating leadership transitions.

We specialize in placing C-suite executives and functional heads at companies navigating critical inflection points: pre-IND, crossover rounds, Phase II readouts, pre-IPO structuring, and public company transitions. Our mandates span organizations of every scale — from first executive hires at Series A companies to C-suite upgrades at publicly traded large pharma.

Operating as a high-touch alternative to global firms, we deliver sector depth, board fluency, and disciplined execution without institutional bureaucracy. Search, to us, is not transactional — it is strategic risk management.

Founded and led by Jason Stewart, Blake & Michaels maintains active relationships across clinical KOLs and physician-scientists, venture syndicate members, and board directors in oncology, rare and orphan disease, and advanced modalities — giving us the proximity to surface candidates who are rarely visible through conventional search channels.

Whether our client is a Series A biotech structuring its first clinical team, a mid-sized company preparing for a crossover round, or a large pharma organization replacing a departing CMO, we bring the same discipline: calibrated success profiles, capital-aware strategy, and high-signal candidate evaluation.

Venture-Backed Biotech
Series A through pre-IPO — first executive hires to crossover structuring.
Mid-Sized Biopharma
Development-stage and commercial-stage companies scaling clinical and functional leadership.
Large Pharma
Established organizations requiring discrete, high-urgency C-suite and functional head placement.
Therapeutic Areas & Modalities
Oncology
Solid tumors, hematologic malignancies, immuno-oncology, ADCs, and precision medicine platforms across early and late-stage development.
Rare & Orphan Disease
Gene therapy, enzyme replacement, RNA-targeted therapies, and small molecule approaches in rare metabolic, neurological, and genetic conditions.
Neuroscience
CNS disorders, neurodegeneration, psychiatric conditions, and neurological rare diseases spanning small molecules and biologics.
Immunology & Inflammation
Autoimmune, inflammatory, and fibrotic disease across biologics, small molecules, and next-generation targeted therapies.
Cardiovascular & Metabolic
Cardiometabolic disease, heart failure, and lipid disorders — including CRISPR and RNA-based modalities entering the space.
Infectious Disease & Vaccines
Antiviral, antibacterial, and vaccine development across mRNA platforms, biologics, and small molecule antivirals.
Modalities Small MoleculeCell & Gene TherapymRNA & RNA-TargetedBiologics & AntibodiesADCCRISPR & Gene EditingRadiopharmaceuticalsEnzyme ReplacementCombination ProductsOligonucleotides
02 — Approach

Where We Differentiate

02
1
Clinical Development Leadership Vertical

Our core niche. We identify and secure leaders whose scientific credibility and strategic timing align with your regulatory and capital objectives.

  • Chief Medical Officers
  • Heads of Clinical Development
  • Pharmacovigilance & Drug Safety Leaders
  • Translational & Regulatory Medicine Executives
  • IND timing & Phase I–III transition specialists
  • Combination product & modality complexity
2
Capital-Aware Search Strategy

We operate with fluency in capital formation dynamics — structuring search mandates around investor signaling, governance optics, and valuation staging.

  • Series A / B / C buildout structuring
  • Pre-IPO executive composition
  • Public company governance optics
  • Compensation benchmarking vs. valuation stage
  • Investor & banker signaling dynamics
3
Network Density Over Database Volume

Our advantage is proximity — not scale. Candidates engage with us because of trust, not volume outreach. We maintain active relationships, not archived contacts.

  • Clinical KOLs and physician-scientists
  • Emerging biotech C-suite operators
  • Venture partners and syndicate members
  • Board directors across key therapeutic areas
03 — Timing

Critical Engagement Points

03

We are strongest when leadership timing directly impacts enterprise value. These are the roles where early, precise placement has the greatest downstream effect on regulatory trajectory, capital formation, and investor confidence.

Clinical Development
Chief Medical Officer

The CMO is the most capital-sensitive hire in early-stage biopharma. Scientific credibility, regulatory fluency, and investor-facing communication skills must align simultaneously — making timing and candidate calibration critical to downstream valuation events.

Capital Formation
Chief Financial Officer

CFO placement is never just a finance function. At pivotal funding stages, the right CFO shapes the financial narrative, builds governance infrastructure, and positions the company for investor scrutiny — making the hire inseparable from capital strategy.

Regulatory & Safety
Head of Drug Safety / Pharmacovigilance

Establishing pharmacovigilance leadership at the right inflection point reduces regulatory exposure, signals operational maturity to partners and regulators, and protects the integrity of clinical programs under increasing complexity.

Platform & Pipeline
Chief Scientific Officer

CSO placement requires alignment between scientific vision, modality depth, and the strategic narrative presented to licensing, partnership, or M&A counterparties. We identify scientists who can lead internally and represent credibly externally.

Public Markets & Scale
C-Suite Upgrade / Transition

Leadership transitions at public companies demand executives with governance experience, investor fluency, and the operational credibility to execute on an accelerated regulatory and commercial path — where visibility and accountability are at their highest.

04 — Footprint

Geographic Reach

04

Headquartered in San Diego — the epicenter of U.S. biopharmaceutical innovation — Blake & Michaels operates bi-coastally with national search reach across the country's major life sciences and financial hubs.

Our active market presence spans San Diego, Los Angeles, San Francisco, New York, New Jersey, and Boston — covering the country's primary nodes of biopharma capital formation, clinical development, and executive talent.

We do not limit mandates by geography. We operate wherever the company, the candidate, or the capital requires.

Headquarters
San Diego, CA
Presence
Bi-Coastal + National
Key Markets
6 U.S. Hubs
05 — Client Experience

What Our Clients Say

05

Across therapeutic areas, company stages, and geographies — our clients return and refer because of outcomes, not promises.

Top 10 Global Pharma
Building an oncology clinical safety team where institutional search had stalled — placing three physicians in a single, high-touch engagement.

A referral from a trusted executive who had worked with us before. We partnered closely with the therapeutic business head to identify not just qualified physicians, but individuals positioned to grow quickly within the organization.

Outcome: Two of three physicians placed received promotions within 6–9 months. The engagement led to a direct referral to Executive Talent Acquisition.
Therapeutic Business Head
Los Angeles, CA
Top 5 Private Equity Portfolio
A CHRO mandate built around culture, diversity, and long-term organizational fit — not simply filling a seat.

We engaged as a genuine search partner — conducting deep discovery, participating in every interview debrief, and presenting a preferred candidate whose profile reflected the CHRO's vision for a more collaborative, diverse leadership team.

"I have thoroughly enjoyed working with you and will certainly refer you to anyone. I look forward to our continued partnership."

Chief Human Resource Officer
Boston, MA
Startup — First Drug Approval
A first-in-class drug approval creating an urgent, unplanned need for post-market pharmacovigilance leadership — resolved in under 40 days.

Referred through our network after two prior agencies had worked the mandate for 4–5 months without success. We identified the right strategic fit quickly — bringing both urgency and precision to a hire that would define the company's post-launch safety posture.

"This was a seamless process and we really appreciate and value your support."

VP of People
San Francisco, CA
06 — Philosophy

Why Blake & Michaels

Leadership at the wrong time is expensive.
Credibility with regulators and investors matters.
Search is not transactional — it is strategic risk management.

We embed capital-market thinking, board-level judgment, and therapeutic area depth into every search mandate — because the cost of a missed hire at a critical inflection point isn't measured in recruiter fees. It's measured in valuation, timeline, and credibility.

Begin a Conversation
07 — Contact

Initiate a Mandate

07

If you are a biopharmaceutical company approaching an inflection point and believe leadership quality will determine your trajectory — we are ready to engage. All initial conversations are confidential.

San Diego, California
Confidentiality Note

All engagements and initial inquiries are handled with complete confidentiality. We do not disclose client mandates, candidate identities, or search activity without explicit authorization from both parties.